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Code
OSK00007G
$240USD
ID Tag
Rb857-290309-G
Immunogen
A synthetic peptide from aa region 330-379 of human KCNJ10 conjugated to blue carrier protein was used as the antigen.
Accession
Also known
ATP-sensitive inward rectifier potassium channel 10, Potassium channel, inwardly rectifying subfamily J member 10, Inward rectifier K(+) channel Kir1.2, ATP-dependent inwardly rectifying potassium channel Kir4.1
Target
FUNCTION: May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.
Subcellular location: Membrane, Multi-pass membrane protein.
Subcellular location: Membrane, Multi-pass membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Shuck M.E, et al. J. Biol. Chem. 272:586-593(1997)
2. Schoots O, et al. Cell. Signal. 11:871-883(1999)
2. Schoots O, et al. Cell. Signal. 11:871-883(1999)
Limitation
For research use only
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Code
OSK00007G
$240USD
Unit size
500 µg
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
IgG
Clonality
Polyclonal
Isotype
Polyclonal, IgG
Applications
IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for KCNJ10.
Spcs X-react.
Rat, mouse, human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com
Code
OSK00007G
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
⚬ Products
Rabbit antibody to KCNJ10 (330-379)
