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Code
OSS00108W
$240USD
ID Tag
Rb746-061208-WS
Immunogen
A synthetic peptide from the 1t extracellular domain of mouse 5HT3A receptor conjugated to blue carrier protein was used as the antigen. The peptide shares 86% identity with rat sequence.
Accession
Also known
5-HT3R, 5-HT-3, Serotonin receptor 3A, Htr3a, 5ht3, Htr3, Serotonin gated ion channel receptor
Target
FUNCTION: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Subcellular location: Cell junction ⺠synapse ⺠postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Tissue specificity: Expressed in central and peripheral neurons.
Induction: By nerve growth factor in PC12 cells.
Subcellular location: Cell junction ⺠synapse ⺠postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Tissue specificity: Expressed in central and peripheral neurons.
Induction: By nerve growth factor in PC12 cells.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Maricq A.V, et al. Science 254:432-437(1991)
2. Uetz P, et al. FEBS Lett. 339:302-306(1994)
2. Uetz P, et al. FEBS Lett. 339:302-306(1994)
Limitation
For research use only
Code
OSS00108W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for 5HT3A receptor.
Spcs X-react.
Mouse. Other species not yet tested but expected to work in rat.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Code
OSS00108W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OSS00108W
$240USD
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WB on mouse brain lysate using Rabbit antibody to 5-HT3A R (OSS00108W) at 1:500 dilution. Incubated 30 min at RT with shake. Blocking: 0.5% LFDM in 1x PBS containing 0.1% Tween-20 |
⚬ Products
Rabbit antibody to 5HT3A R
