Sh18-111107-WS

A synthetic peptide from human Olfactory Marker Protein (OMP) conjugated to an immunogenic carrier protein has been used as the antigen.

Olfactory neuronal-specific protein

Olfactory marker protein (OMP) is an abundant, 19-kDa, cytosolic protein that is almost exclusively expressed in mature, functioning, olfactory neurons but not in the neural precursor basal cells. The OMP gene structure and protein sequence are highly conserved between mouse, rat and human. Its tissue-specific expression in the receptor cells together with the results of the mouse knockout studies show that OMP represents a novel modulatory component of the odor detection/signal transduction cascade. FUNCTION: May act as a modulator of the olfactory signal-transduction cascade. SUBUNIT: Interacts with BEX1 and BEX2. SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICITY: Uniquely associated with mature olfactory receptor neurons. SIMILARITY: Belongs to the olfactory marker protein family.

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

12 months after reconstitution

This item will be shipped to you at ambient temperature in a lyophilised form.

1. Margolis, F. L. Scand J Immunol Suppl. 9: 181-99 (1982)
2. Moriya-Ito et al. Chem. Senses 30 (2), 111-119 (2005)
3. Baldisseri et al. J. Mol. Biol. 319 (3), 823-837 (2002)
4. Rogers et al. Proc. Natl. Acad. Sci. U.S.A. 84 (6), 1704-1708 (1987)
5. Grillo, M. et al. Int J Dev Neurosci. 14 (7-8), 813-22 (1996)
6. Margolis, J. W. et al. J Biomol NMR. 33 (1), 63-8 (2005)

For research use only

	Code Product Name OSO00007G Sheep antibody to OMP

100 µl

Unconjugated antibody

Sheep

Whole serum

Polyclonal

Polyclonal, whole serum

IHC, WB. Use at a dilution of 1 : 300 to 1 : 2000. The optimal dilution should be determined by the end user. For IHC, Zamboni's or 4% PFA fixatives are recommended.

Highly specific for mature olfactory neurons (including axon and terminals).

Human

Lyophilised

Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

- Click to download the Data Sheet

- Click to download the Material Safety Data Sheet

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This item is in our stock. The expected delivery time is within 5 business days worldwide.