| Code |
OSV00002G |
| ID Tag |
Rb551-290608-G |
| Ordering info |
Order online using the shopping cart ("Add to Cooler"), by email to
sales@osenses.com
or fax to 61-8-827 0 8586 and pay via PayPal by
MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors.
This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
 |
| Unit size |
500 µg |
| Immunogen |
A synthetic peptide as a part of human, mouse and rat VACHT conjugated to an immunogenic carrier protein was used as the immunogen. |
| Conjugate |
Unconjugated antibody |
| Accession |
VACHT_HUMAN
VACHT_MOUSE
VACHT_RAT |
| Also known as |
Vesicular acetylcholine transporter, solute carrier family 18 member 3, SLC18A3, MGC12716 |
| Background |
FUNCTION: Involved in acetylcholine transport into synaptic vesicles.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: High expression in all major cholinergic cell groups, including peripheral postganglionic parasympathetic cells, preganglionic sympathetic and parasympathetic cells, ventral spinal cord and brainstem motoneurons, cell groups in the basal forebrain, the habenula and the corpus striatum. Weakly expressed in the cortex and hippocampus.
VACHT is also present in the olfactory bulb, nucleus of the lateral olfactory tract, olfactory tubercle.
SIMILARITY: Belongs to the major facilitator superfamily. Vesicular transporter family. |
| Host |
NZ white rabbit |
| Purity |
IgG |
| Clonality |
Polyclonal |
| Isotype |
Polyclonal, IgG |
| Applications |
IHC, WB. A working concentration of 1-10 µg/ml is recommended. The optimal concentration should be determined by the end user. |
| Specificity |
Appears to be specific for VACHT. |
| Spcs X-react. |
Human, mouse, rat. Other species not yet tested. |
| Format |
Lyophilised |
| Reconstitution |
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage |
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Expiry Date |
12 months after reconstitution |
| Transportation |
This item will be shipped to you at ambient temperature in a lyophilised form. |
| References |
1. Ichikawa T, et al. J Chem Neuroanat. 13(1):23-39(1997).
2. Roghani A, et al. Proc. Natl. Acad. Sci. U.S.A. 91:10620-10624(1994).
3. Erickson J.D, et al. J. Biol. Chem. 269:21929-21932(1994).
4. Bejanin S, et al. J. Biol. Chem. 269:21944-21947(1994). |
| Limitation |
For research use only |
Primary Antibodies
