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Code
ID Tag
Immunogen
A synthetic peptide from the c-terminal of mouse TRPC7 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares a significant identity with TRPPC3 and TRPC6 of mouse, rat and human origins.
Accession
Also known
Short transient receptor potential channel 7, transient receptor potential cation channel, subfamily C, member 7, TrpC7, Transient receptor protein 7, Mtrp7, Receptor-activated cation channel TRP7
Target
FUNCTION: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG). May also be activated by intracellular calcium store depletion.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Mori Y, et al. NeuroReport 9:507-515(1998).
2. Zhu X, et al. Cell 85:661-671(1996).
3. Yamazaki,K, et al. Genomics 51 (2), 303-305 (1998).
4. Nakayama,H, et al. FASEB J. 20 (10), 1660-1670 (2006).
5. Li,M.Z, et al. Dev. Biol. 292 (2), 555-564 (2006).
2. Zhu X, et al. Cell 85:661-671(1996).
3. Yamazaki,K, et al. Genomics 51 (2), 303-305 (1998).
4. Nakayama,H, et al. FASEB J. 20 (10), 1660-1670 (2006).
5. Li,M.Z, et al. Dev. Biol. 292 (2), 555-564 (2006).
Limitation
For research use only
Code
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Appears to recognise TRPC3, TRPC6 and TRPC7.
Spcs X-react.
Mouse, human, rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Code
PDF Data Sheet
- Click to download the Data SheetMSDS
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