Rabbit antibody to T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1, TIAM1): whole serum

$240USD

Code	OST00085W
ID Tag	Rb330-200308-WS
Ordering info	Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors. This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
Unit size	100 µl
Immunogen	A synthetic peptide as a part of human, mouse T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1, TIAM1) conjugated to an immunogenic carrier protein was used as the immunogen.
Conjugate	Unconjugated antibody
Accession	TIAM1_HUMAN TIAM1_MOUSE
Also known as	TIAM-1, TIAM1
Background	FUNCTION: Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. SUBUNIT: Interacts with BAIAP2. TISSUE SPECIFICITY: Found in virtually all analyzed tumor cell lines including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.
Host	NZ white rabbit
Purity	Whole serum
Clonality	Polyclonal
Isotype	Polyclonal, whole serum
Applications	IHC, WB. A dilution of 1 : 300 to 1 : 3000 is recommended. The optimal dilution should be determined by the end user.
Specificity	Appears to be specific for TIAM1.
Spcs X-react.	Human, mouse. Other species not yet tested.
Format	Lyophilised
Reconstitution	Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Transportation	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Habets G.G.M, et al. Oncogene 10:1371-1376(1995). 2. Hattori M, et al. Nature 405:311-319(2000). 3. Michiels F, et al. Nature 375:338-340(1995). 4. Habets G.G.M, et al. Cytogenet. Cell Genet. 70:48-51(1995). 5. Connolly B.A, et al. Mol. Cell. Biol. 25:4602-4614(2005). 6. Sjoeblom T, et al. Science 314:268-274(2006). 7. Cao L, et al. J. Immunol. 179:5864-5876(2007). 8. Worthylake D.K, et al. Nature 408:682-688(2000).
Limitation	For research use only

Rabbit antibody to T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1, TIAM1): whole serum

IF on 1 day- old mouse cortical cell culture using Rabbit antibody to T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1, TIAM1): whole serum (OST00085W) at 1: 2000 dilution. DAPI counter stained.

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Associated Products

Code	Product Name
OST00086G	Rabbit antibody to T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1, TIAM1): IgG