SUMO 1 antibody, SUMO-1 antibody, SUMO1 antibody

Rabbit antibody to n-terminal of SUMO 1 (SUMO-1, Small ubiquitin related modifier 1): IgG

$240USD

Code	OSS00110G
ID Tag	Rb767-140209-G
Ordering info	Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors. This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
Unit size	500 µg
Immunogen	A synthetic peptide from the n-terminal of rat SUMO 1 (SUMO-1, Small ubiquitin related modifier 1) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in human, mouse and chicken.
Conjugate	Unconjugated antibody
Accession	SUMO1_RAT SUMO1_HUMAN SUMO1_MOUSE SUMO1_CHICKEN
Also known as	Small ubiquitin-related modifier 1, SUMO-1, Sumo1
Background	Function: Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4 Subcellular location: Nucleus. Cytoplasm Post-translational modification: Cleavage of precursor form by SENP1 or SENP2 is necessary for function.
Host	NZ white rabbit
Purity	IgG
Clonality	Polyclonal
Isotype	Polyclonal, IgG
Applications	IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Specificity	Specific for SUMO 1.
Spcs X-react.	Rat, mouse, human. Other species not yet tested.
Format	Lyophilised
Reconstitution	Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Transportation	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Um J.W, et al. J. Neurosci. Res. 84:1543-1554(2006) 2. Shao R, et al. FEBS Lett. 569:293-300(2004) 3. Carninci P, et al. Science 309:1559-1563(2005)
Limitation	For research use only

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MSDS	- Click to download the Material Safety Data Sheet

Associated Products

Code	Product Name
OSS00109W	Rabbit antibody to n-terminal of SUMO 1 (SUMO-1, Small ubiquitin related modifier 1): whole serum