CNG4 antibody, CNG channel alpha-4 antibody, CNG-4 antibody, CNG 4 antibody

Rabbit antibody to n-terminal region of CNG channel alpha-4 (CNG4, CNGA4): whole serum

$240USD

Code	OSC00173W
ID Tag	Rb1047-020809-WS
Ordering info	Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors. This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
Unit size	100 µl
Immunogen	A synthetic peptide from the n-terminal region of mouse CNG channel alpha-4 (CNG4, CNGA4) conjugated to an immunogenic carrier protein was used as the antigen.
Conjugate	Unconjugated antibody
Accession	CNGA4_MOUSE CNGA4_RAT
Also known as	CNGA4, cGMP-gated cation channel alpha-4, CNG-4, CNG4, Cyclic nucleotide-gated channel alpha-4, Cyclic nucleotide-gated channel, photoreceptor, Cyclic nucleotide gated cation channel 3, Cone photoreceptor cGMP-gated channel subunit alpha, CNCG4, CNG 4
Background	FUNCTION: Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection. Tissue specificity: Olfactory neurons
Host	NZ white rabbit
Purity	Whole serum
Clonality	Polyclonal
Isotype	Polyclonal, whole serum
Applications	IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity	Specific for CNGA4.
Spcs X-react.	Mouse, rat. Other species not yet tested.
Format	Lyophilised
Reconstitution	Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Transportation	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Carninci P, et al. Science 309:1559-1563(2005) 2. Munger S.D, et al. Science 294:2172-2175(2001) 3. Kelliher K.R, et al. Proc. Natl. Acad. Sci. U.S.A. 100:4299-4304(2003)
Limitation	For research use only

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