Rabbit antibody to rat, mouse Syntaxin-7 (STX7, Syn7, Syntaxin 7): whole serum

$240USD

Code	OSS00012W
ID Tag	Rb307-200308-WS
Ordering info	Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors. This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
Unit size	100 µl
Immunogen	A synthetic peptide as a part of rat, mouse Syntaxin-7 (STX7, Syn7, Syntaxin 7) conjugated to an immunogenic carrier protein was used as the immunogen.
Conjugate	Unconjugated antibody
Accession	STX7_RAT STX7_MOUSE
Also known as	Syntaxin-7, STX7, Syn7
Background	FUNCTION: May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes. SUBUNIT: Forms a SNARE complex with VTI1B, STX8 and VAMP8 which functions in the homotypic fusion of late endosomes. Interacts with VPS33A. Found in a complex with VAMP8 and VTI1B in the liver. Part of the SNARE core complex containing VAMP8, STX8 and VTI1B. Interacts with VPS11, VPS16 and VPS18. SUBCELLULAR LOCATION: Early endosome membrane; Single-pass type IV membrane protein.
Host	NZ white rabbit
Purity	Whole serum
Clonality	Polyclonal
Isotype	Polyclonal, whole serum
Applications	IHC, WB. A dilution of 1 : 300 to 1 : 3000 is recommended. The optimal dilution should be determined by the end user.
Specificity	Specific for Syntaxin-7.
Spcs X-react.	Rat, mouse. Other species not yet tested.
Format	Lyophilised
Reconstitution	Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Transportation	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Wong S.H, et al. J. Biol. Chem. 273:375-380(1998). 2. Antonin W, et al. EMBO J. 19:6453-6464(2000). 3. Pryor P.R, et al. EMBO Rep. 5:590-595(2004). 4. Ballif B.A, et al. Mol. Cell. Proteomics 3:1093-1101(2004). 5. Munton R.P, et al. Mol. Cell. Proteomics 6:283-293(2007). 6. Villen J, et al. Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007). 7. Antonin W, et al. Nat. Struct. Biol. 9:107-111(2002).
Limitation	For research use only

IHC on rat spinal cord (dorsal horn) using Rabbit antibody to rat, mouse Syntaxin-7 (STX7, Syn7, Syntaxin 7): whole serum (OSS00012W) at 1 : 1000 dilution. Pre-absorption of the antibody with the immunising peptide completely abolishes the immunostaining (not shown).

IHC on rat trigeminal nerve using Rabbit antibody to rat, mouse Syntaxin-7 (STX7, Syn7, Syntaxin 7): whole serum (OSS00012W) at 1 : 1000 dilution. Pre-absorption of the antibody with the immunising peptide completely abolishes the immunostaining (not shown).

IHC on rat spinal cord (central canal) using Rabbit antibody to rat, mouse Syntaxin-7 (STX7, Syn7, Syntaxin 7): whole serum (OSS00012W) at 1 : 1000 dilution. Pre-absorption of the antibody with the immunising peptide completely abolishes the immunostaining (not shown).

IF on 1 day- old mouse cortical cell culture using Rabbit antibody to rat, mouse Syntaxin-7 (STX7, Syn7, Syntaxin 7): whole serum (OSS00012W) at 1: 2000 dilution. DAPI counter stained.

WB on rat brain lysate using Rabbit antibody to rat, mouse Syntaxin-7 (STX7, Syn7, Syntaxin 7): whole serum (OSS00012W) at 1 : 1000 dilution. Pre-absorption of the antibody with the immunising peptide abolishes the detected band.

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Associated Products

Code	Product Name
OSS00030W	Rabbit antibody to human Syntaxin-7 (STX7, Syn7, Syntaxin 7): whole serum