Rabbit antibody to rat, mouse Synaptosomal-associated protein 25 (SNAP-25, SNAP25, SEC9, RIC-4): whole serum

$240USD

Code	OSS00033W
ID Tag	Rb321-200308-WS
Ordering info	Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors. This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
Unit size	100 µl
Immunogen	A synthetic peptide as a part of rat, mouse Synaptosomal-associated protein 25 (SNAP-25, SNAP25, SEC9, RIC-4) conjugated to an immunogenic carrier protein was used as the immunogen.
Conjugate	Unconjugated antibody
Accession	SNAP25_RAT SNAP25_MOUSE
Also known as	SNAP-25, Synaptosomal-associated 25 kDa protein, SNAP25, RIC4, SEC9, SNAP, RIC-4, Super protein, SUP
Background	FUNCTION: t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. SUBUNIT: Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds CPLX1. Interacts with TRIM9, RIMS1, SNAP25BP and HGS. Binds STXBP6. Found in a ternary complex with STX1A and VAMP8. Found in a complex containing SYT1, SV2B and syntaxin-1. SUBCELLULAR LOCATION: Membrane; Lipid-anchor. Cell junction, synapse, synaptosome. Note: Membrane association requires palmitoylation. TISSUE SPECIFICITY: Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum.
Host	NZ white rabbit
Purity	Whole serum
Clonality	Polyclonal
Isotype	Polyclonal, whole serum
Applications	IHC, WB. A dilution of 1 : 300 to 1 : 3000 is recommended. The optimal dilution should be determined by the end user.
Specificity	Appears to be specific for SNAP-25.
Spcs X-react.	Rat, mouse. Other species not yet tested.
Format	Lyophilised
Reconstitution	Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Transportation	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Madison D.L, et al. J. Neurochem. 72:988-998(1999). 2. Hess D.T, et al. J. Neurosci. 12:4634-4641(1992). 3. Hepp R, et al. FEBS Lett. 532:52-56(2002). 4. Jacobsson G, et al. Brain Res. Mol. Brain Res. 37:49-62(1996). 5. Bean A.J, et al. Nature 385:826-829(1997). 6. Fasshauer D, et al. J. Biol. Chem. 274:15440-15446(1999). 7. Coppola T, et al. J. Biol. Chem. 276:32756-32762(2001). 8. Scales S.J, et al. J. Biol. Chem. 277:28271-28279(2002). 9. Sutton R.B, et al. Nature 395:347-353(1998). 10. Ernst J.A, et al. J. Biol. Chem. 278:8630-8636(2003).
Limitation	For research use only

WB on rat brain lysate using Rabbit antibody to rat, mouse Synaptosomal-associated protein 25 (SNAP-25, SNAP25, SEC9, RIC-4): whole serum (OSS00033W) at 1 : 1000 dilution. Pre-absorption of the antibody with the immunising peptide completely abolishes the detected band.

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Associated Products

Code	Product Name
OSS00043G	Rabbit antibody to human Synaptosomal-associated protein 25 (SNAP-25, SNAP25, SEC9, RIC-4): IgG
OSS00032W	Rabbit antibody to human Synaptosomal-associated protein 25 (SNAP-25, SNAP25, SEC9, RIC-4): whole serum
OSS00042G	Rabbit antibody to rat, mouse Synaptosomal-associated protein 25 (SNAP-25, SNAP25, SEC9, RIC-4): IgG