Rabbit antibody to rat, mouse Synapsin-3 (Synapsin 3, Syn3, Synapsin III): whole serum

$240USD

Code	OSS00018W
ID Tag	Rb308-200308-WS
Ordering info	Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors. This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
Unit size	100 µl
Immunogen	A synthetic peptide as a part of rat, mouse Synapsin-3 (Synapsin 3, Syn3, Synapsin III) conjugated to an immunogenic carrier protein was used as the immunogen.
Conjugate	Unconjugated antibody
Accession	SYN3_RAT SYN3_MOUSE
Also known as	Synapsin 3, Syn3, Synapsin III
Background	FUNCTION: May be involved in the regulation of neurotransmitter release and synaptogenesis. Binds ATP with high affinity and ADP with a lower affinity. This is consistent with a catalytic role of the C-domain in which ADP would be dissociated by cellular ATP after bound ATP was hydrolyzed. SUBUNIT: Interacts with CAPON. SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note: Peripheral membrane protein localized to the cytoplasmic surface of synaptic vesicles. MISCELLANEOUS: Regulated by calcium. Calcium inhibits ATP binding to the C-domain.
Host	NZ white rabbit
Purity	Whole serum
Clonality	Polyclonal
Isotype	Polyclonal, whole serum
Applications	IHC, WB. A dilution of 1 : 300 to 1 : 3000 is recommended. The optimal dilution should be determined by the end user.
Specificity	Specific for Synapsin-3.
Spcs X-react.	Rat, mouse. Other species not yet tested.
Format	Lyophilised
Reconstitution	Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Transportation	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Ehringer M.A, et al. Mamm. Genome 12:657-663(2001). 2. Trinidad J.C, et al. Mol. Cell. Proteomics 5:914-922(2006). 3. Munton R.P, et al. Mol. Cell. Proteomics 6:283-293(2007). 4. Hosaka M, et al. J. Biol. Chem. 273:13371-13374(1998). 5. Jaffrey S.R, et al. Proc. Natl. Acad. Sci. U.S.A. 99:3199-3204(2002).
Limitation	For research use only

IHC on rat sciatic nerve using Rabbit antibody to rat, mouse Synapsin-3 (Synapsin 3, Syn3, Synapsin III): whole serum (OSS00018W) at 1 : 1000 dilution. Pre-absorption of the antibody with the immunising peptide completely abolishes the immunostaining (not shown).

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