| Code |
OSB00017W |
| ID Tag |
Rb543-290608-WS |
| Ordering info |
Order online using the shopping cart ("Add to Cooler"), by email to
sales@osenses.com
or fax to 61-8-827 0 8586 and pay via PayPal by
MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors.
This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
 |
| Unit size |
100 µl |
| Immunogen |
A synthetic peptide from n-terminal region of human mature BDNF (Brain derived neurotrophic factor) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in many other species including rat, mouse, zebra fish and xenopus. |
| Conjugate |
Unconjugated antibody |
| Accession |
BDNF_HUMAN
BDNF_RAT
BDNF_MOUSE |
| Also known as |
Brain-derived neurotrophic factor, BDNF, Abrineurin |
| Background |
FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB.
SUBCELLULAR LOCATION: Secreted. |
| Host |
NZ white rabbit |
| Purity |
Whole serum |
| Clonality |
Polyclonal |
| Isotype |
Polyclonal, whole serum |
| Applications |
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Specificity |
Specific for mature BDNF. |
| Spcs X-react. |
Human, rat, mouse. Other species not yet tested. |
| Format |
Lyophilised |
| Reconstitution |
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage |
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Expiry Date |
12 months after reconstitution |
| Transportation |
This item will be shipped to you at ambient temperature in a lyophilised form. |
| References |
1. Maisonpierre P.C, et al. Genomics 10:558-568(1991).
2. Ohara O, et al. Gene 121:383-386(1992).
3. Yancopoulos G.D, et al. Cold Spring Harb. Symp. Quant. Biol. 55:371-379(1990).
4. Liu Q.-R, et al. Brain Res. 1067:1-12(2006).
5. Aid T, et al. J. Neurosci. Res. 85:525-535(2007).
6. Timmusk T, et al. Neuron 10:475-489(1993).
7. Hallboeoek F, et al. Neuron 6:845-858(1991). |
| Limitation |
For research use only |
Primary Antibodies 
