SNF8 antibody, EAP30 antibody, ESCRT-II complex subunit VPS22 antibody

Rabbit antibody to internal region of Vacuolar sorting protein SNF8: IgG

$240USD

Code	OSV00024G
ID Tag	Rb691-060908-G
Ordering info	Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors. This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
Unit size	500 µg
Immunogen	A synthetic peptide from the internal region of human Vacuolar-sorting protein SNF8 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat, mouse and xenopus.
Conjugate	Unconjugated antibody
Accession	SNF8_HUMAN SNF8_RAT SNF8_MOUSE SNF8_XENOPUS
Also known as	EAP30, ELL-associated protein of 30 kDa, ESCRT-II complex subunit VPS22
Background	FUNCTION: Component of the ESCRT-II complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL. SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
Host	NZ white rabbit
Purity	IgG
Clonality	Polyclonal
Isotype	Polyclonal, IgG
Applications	IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Specificity	Specific for SNF8.
Spcs X-react.	Mouse, rat, human. Other species not yet tested.
Format	Lyophilised
Reconstitution	Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Transportation	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Schmidt A.E, et al. J. Biol. Chem. 274:21981-21985(1999). 2. von Schwedler U.K, et al. Cell 114:701-713(2003). 3. Schmidt A.E, et al. J. Biol. Chem. 274:21981-21985(1999). 4. Kamura T, et al. J. Biol. Chem. 276:16528-16533(2001). 5. Carninci P, et al. Science 309:1559-1563(2005).
Limitation	For research use only

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Associated Products

Code	Product Name
OSV00023W	Rabbit antibody to internal region of Vacuolar sorting protein SNF8: whole serum
OSV00050W	Sheep antibody to internal region of Vacuolar sorting protein SNF8 (EAP30): whole serum