| Code |
OSN00024W |
| ID Tag |
Rb885-290309-WS |
| Ordering info |
Order online using the shopping cart ("Add to Cooler"), by email to
sales@osenses.com
or fax to 61-8-827 0 8586 and pay via PayPal by
MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors.
This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
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| Unit size |
100 µl |
| Immunogen |
A synthetic peptide from internal region of human Nogo (RTN4, Neurite outgrowth inhibitor, Reticulon-4) conjugated to an immunogenic carrier protein was used as the antigen. |
| Conjugate |
Unconjugated antibody |
| Accession |
NOGO_HUMAN
NOGO_RAT
NOGO_MOUSE |
| Also known as |
RTN4, Neurite outgrowth inhibitor, Reticulon-4, Nogo protein, Foocen, Neuroendocrine-specific protein, NSP, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5 |
| Background |
Function: Potent neurite growth inhibitor in vitro and plays a role both in the restriction of axonal regeneration after injury and in structural plasticity in the CNS.
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Note: Anchored to the membrane of the endoplasmic reticulum through 2 putative transmembrane domains.
Tissue specificity: Isoform 1 is specifically expressed in brain and testis and weakly in heart and skeletal muscle. Isoform 2 is widely expressed except for the liver. Isoform 3 is expressed in brain, skeletal muscle and adipocytes. Isoform 4 is testis-specific. |
| Host |
NZ white rabbit |
| Purity |
Whole serum |
| Clonality |
Polyclonal |
| Isotype |
Polyclonal, whole serum |
| Applications |
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Specificity |
Specific for Nogo. |
| Spcs X-react. |
Human, rat, mouse. Other species not yet tested. |
| Format |
Lyophilised |
| Reconstitution |
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage |
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Expiry Date |
12 months after reconstitution |
| Transportation |
This item will be shipped to you at ambient temperature in a lyophilised form. |
| References |
1. Yang J, et al. Cytogenet. Cell Genet. 88:101-102(2000)
2. Prinjha R, et al. Nature 403:383-384(2000)
3. Tagami S, et al. Oncogene 19:5736-5746(2000)
4. Zhou Z.M, et al. Reproduction 123:227-234(2002)
5. Sjoeblom T, et al. Science 314:268-274(2006) |
| Limitation |
For research use only |
Primary Antibodies 
