Mannose 6 Phosphate Receptor (Cation dependent) antibody, MPRD antibody

Rabbit antibody to internal region of MPRD (Cation dependent mannose-6-phosphate receptor): IgG

$240USD

Code	OSM00062G
ID Tag	Rb660-060908-G
Ordering info	Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors. This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
Unit size	500 µg
Immunogen	A synthetic peptide from the internal region of mouse MPRD (Cation dependent mannose-6-phosphate receptor) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat.
Conjugate	Unconjugated antibody
Accession	MPRD_MOUSE MPRD_RAT
Also known as	CD Man-6-P receptor, CD-MPR, 46 kDa mannose 6-phosphate receptor, MPR 46, Cation-dependent mannose-6-phosphate receptor, M6pr, 46mpr
Background	FUNCTION: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. SUBUNIT: Homodimer. Binds GGA1, GGA2 and GGA3. SUBCELLULAR LOCATION: Lysosome membrane; Single-pass type I membrane protein.
Host	NZ white rabbit
Purity	IgG
Clonality	Polyclonal
Isotype	Polyclonal, IgG
Applications	IHC, WB. Use at a concentration of 10-50 µg/ml. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity	Specific for MPRD.
Spcs X-react.	Mouse, rat. Other species not yet tested.
Format	Lyophilised
Reconstitution	Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Transportation	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Ludwig T, et al. J. Biol. Chem. 267:12211-12219(1992). 2. Koester A, et al. Biol. Chem. Hoppe-Seyler 372:297-300(1991). 3. Ma Z, et al. J. Biol. Chem. 266:10589-10595(1991). 4. Szebenyi G, et al. J. Biol. Chem. 266:5534-5539(1991).
Limitation	For research use only

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Associated Products

Code	Product Name
OSM00057W	Rabbit antibody to internal region of MPRD (Cation dependent mannose-6-phosphate receptor): whole serum