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Code
OSH00004W
$240USD
ID Tag
Rb642-170808-WS
Immunogen
A synthetic peptide from the internal region of rat HOMER3 (Home3, Vesl-3, Vesl3, Homer-3) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known as
Home3, Homer protein homolog 3, VASP/Ena-related gene up-regulated during seizure and LTP 3, Vesl-3, Vesl3
Target
FUNCTION: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors it aids the coupling of surface receptors to intracellular calcium release.
SUBUNIT: Encodes coiled-coil structures that mediate homo- and heteromultimerization.
SUBCELLULAR LOCATION: Cytoplasm. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Note: Postsynaptic density of neuronal cells.
It may interact with group I metabotropic glutamate receptors and regulate their coupling to membrane ion channels.
SUBUNIT: Encodes coiled-coil structures that mediate homo- and heteromultimerization.
SUBCELLULAR LOCATION: Cytoplasm. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Note: Postsynaptic density of neuronal cells.
It may interact with group I metabotropic glutamate receptors and regulate their coupling to membrane ion channels.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Transportation
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Kammermeier, P. J, et al. J. Neurosci. 20 (19), 7238-7245(2000).
2. Xiao, B, et al. Neuron 21 (4), 707-716(1998).
2. Xiao, B, et al. Neuron 21 (4), 707-716(1998).
Limitation
For research use only
Code
OSH00004W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
Specificity
Specific for Homer3.
Spcs X-react.
Rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Code
OSH00004W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OSH00004W
$240USD
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IF on mouse brain (frozen section) at 1 : 500 dilution using Rabbit antibody to HOMER3 (OSH00004W). |
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IF on mouse brain (frozen section) at 1 : 500 dilution using Rabbit antibody to HOMER3 (OSH00004W). |
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IF on mouse brain (frozen section) at 1 : 500 dilution using Rabbit antibody to HOMER3 (OSH00004W). |
Code
OSH00004W
$240USD
Ordering
Order online using the shopping cart ("Add to Cooler"), by email to
sales@osenses.com
or fax to 61-8-827 0 8586 and pay via PayPal by
MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors.
This item is in our stock. The expected delivery time is within 5 business days worldwide.
This item is in our stock. The expected delivery time is within 5 business days worldwide.
Products
Rabbit antibody to HOMER3
