VPS36 antibody, Vacuolar protein sorting associated protein 36 antibody

Rabbit antibody to internal region of Vacuolar protein-sorting-associated protein 36 (VPS36): whole serum

$240USD

Code	OSV00031W
ID Tag	Rb700-060908-WS
Ordering info	Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors. This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
Unit size	100 µl
Immunogen	A synthetic peptide from the internal region of mouse Vacuolar protein-sorting-associated protein 36 (VPS36) conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat.
Conjugate	Unconjugated antibody
Accession	VPS36_MOUSE VPS36_RAT
Also known as	VPS36
Background	FUNCTION: Component of the ESCRT-II complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. SUBCELLULAR LOCATION: Cytoplasm. Late endosome. Nucleus. NoteL Colocalizes with ubiquitinated proteins on late endosomes.
Host	NZ white rabbit
Purity	Whole serum
Clonality	Polyclonal
Isotype	Polyclonal, whole serum
Applications	IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.
Specificity	Specific for VPS36.
Spcs X-react.	Mouse, rat. Other species not yet tested.
Format	Lyophilised
Reconstitution	Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Transportation	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Carninci P, et al. Science 309:1559-1563(2005). 2. Gibbs R.A, et al. Nature 428:493-521(2004). 3. Kamura T, et al. J. Biol. Chem. 276:16528-16533(2001).
Limitation	For research use only

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Associated Products

Code	Product Name
OSV00032G	Rabbit antibody to internal region of Vacuolar protein-sorting-associated protein 36 (VPS36): IgG