TAS2R44 antibody, T2R44 antibody, T2R53 antibody

Rabbit antibody to human taste receptor, type 2, member 44 (TAS2R44, T2R44, T2R53): whole serum

$240USD

Code	OSR00168W
ID Tag	Rb195.44-251107-WS
Ordering info	Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors. This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
Unit size	100 µl
Immunogen	A synthetic peptide from human taste receptor, type 2, member 44 (TAS2R44, T2R44, T2R53) conjugated to an immunogenic carrier protein was used as the antigen. This antibody is expected to also recognise TAS2R43, TAS2R45 and TAS2R47.
Conjugate	Unconjugated antibody
Accession	TAS2R44_HUMAN
Also known as	Taste receptor type 2 member 44, T2R44, T2R53, TAS2R44
Background	FUNCTION: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. MISCELLANEOUS: Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.
Host	NZ white rabbit
Purity	Whole serum
Clonality	Polyclonal
Isotype	Polyclonal, whole serum
Applications	IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
Specificity	Specific for TAS2R44 (and likely TAS2R43, TAS2R45 and TAS2R47. See the Immunogen).
Spcs X-react.	Human. Other species not yet tested.
Format	Lyophilised
Reconstitution	Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Transportation	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Bufe B, et al. Nat. Genet. 32:397-401(2002). 2. Conte C, et al. Cytogenet. Genome Res. 98:45-53(2002). 3. Kuhn C, et al. J. Neurosci. 24:10260-10265(2004). 4. Chandrashekar J, et al. Cell 100:703-711(2000). 5. Montmayeur J.-P, et al. Curr. Opin. Neurobiol. 12:366-371(2002).
Limitation	For research use only

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