TAS2R10 antibody, T2R10 antibody, human taste receptor, type 2, member 10 antibody

Rabbit antibody to human taste receptor, type 2, member 10 (TAS2R10, T2R10, TRB2): whole serum

$240USD

Code	OSR00158W
ID Tag	Rb186-251107-WS
Ordering info	Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors. This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
Unit size	100 µl
Immunogen	A synthetic peptide from human taste receptor, type 2, member 10 (TAS2R10, T2R10, TRB2) conjugated to an immunogenic carrier protein was used as the antigen.
Conjugate	Unconjugated antibody
Accession	TAS2R10_HUMAN
Also known as	Taste receptor type 2 member 10, T2R10, Taste receptor family B member 2, TRB2, MGC126811, MGC126813
Background	This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. FUNCTION: Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. MISCELLANEOUS: Several bitter taste receptors are expressed in a single taste receptor cell.
Host	NZ white rabbit
Purity	Whole serum
Clonality	Polyclonal
Isotype	Polyclonal, whole serum
Applications	IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity	Specific for TAS2R10.
Spcs X-react.	Human. Other species not yet tested.
Format	Lyophilised
Reconstitution	Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Transportation	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Adler E, et al. Cell 100:693-702(2000). 2. Fischer A, et al. Mol. Biol. Evol. 22:432-436(2005). 3. Hillier L.W, et al. Nature 424:157-164(2003). 4. Chandrashekar J, et al. Cell 100:703-711(2000). 5. Montmayeur J.-P, et al. Curr. Opin. Neurobiol. 12:366-371(2002). 6. Margolskee R.F. J. Biol. Chem. 277:1-4(2002). 7. Zhang Y, et al. Cell 112:293-301(2003).
Limitation	For research use only

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