| Code |
OSA00061G |
| ID Tag |
Rb287-270108-G |
| Ordering info |
Order online using the shopping cart ("Add to Cooler"), by email to
sales@osenses.com
or fax to 61-8-827 0 8586 and pay via PayPal by
MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors.
This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
 |
| Unit size |
500 µg |
| Immunogen |
Synthetic peptides (a pentamer) from human Arg3.1 (ARC) was used as the antigen. |
| Conjugate |
Unconjugated antibody |
| Accession |
Arg3.1/ARC_HUMAN
Arg3.1/ARC_MOUSE
Arg3.1/ARC_RAT |
| Also known as |
Activity-regulated cytoskeleton-associated protein, Activity-regulated gene 3.1 protein homolog, KIAA0278, Arg3.1/ARC, |
| Background |
FUNCTION: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors.
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton. Endosome. Acrosome. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, dendrite. Cell projection, dendritic spine. Cell junction, synapse. Note: associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail. |
| Host |
NZ white rabbit |
| Purity |
IgG |
| Clonality |
Polyclonal |
| Isotype |
Polyclonal, IgG |
| Applications |
IHC. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. |
| Specificity |
Specific for Arg3.1/ARC. |
| Spcs X-react. |
Human, mouse and rat. Other species not yet tested. |
| Format |
Lyophilised |
| Reconstitution |
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage |
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Expiry Date |
12 months after reconstitution |
| Transportation |
This item will be shipped to you at ambient temperature in a lyophilised form. |
| References |
1. Tan J, et al. Neuroscience. 16;145(2):715-26(2007).
2. Link,W, et al. Proc. Natl. Acad. Sci. U.S.A. 92 (12), 5734-5738 (1995).
3. Shepherd J.D, et al. Neuron 52:475-484(2006).
4. Rial Verde E.M, et al. Neuron 52:461-474(2006).
5. Chowdhury S, et al. Neuron 52:445-459(2006). |
| Limitation |
For research use only |
Primary Antibodies 
