NEDD4 antibody, NEDD-4 antibody, NEDD 4 antibody

Rabbit antibody to HECT domain of NEDD4 (NEDD-4, E3 ubiquitin-protein ligase NEDD4): whole serum

$240USD

Code	OSN00011W
ID Tag	Rb710-060908-WS
Ordering info	Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors. This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
Unit size	100 µl
Immunogen	A synthetic peptide from the HECT domain of human NEDD4 (NEDD-4, E3 ubiquitin-protein ligase NEDD4) conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
Conjugate	Unconjugated antibody
Accession	NEDD4_HUMAN NEDD4_RAT NEDD4_MOUSE
Also known as	Neural precursor cell expressed developmentally down-regulated protein 4, E3 ubiquitin-protein ligase NEDD4, NEDD-4
Background	FUNCTION: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. FUNCTION: Involved in the embryonic development and differentiation of the central nervous system. SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICITY: Brain.
Host	NZ white rabbit
Purity	Whole serum
Clonality	Polyclonal
Isotype	Polyclonal, whole serum
Applications	IHC, WB. A dilution of 1: 500 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity	Specific for NEDD4.
Spcs X-react.	Mouse, rat, human. Other species not yet tested.
Format	Lyophilised
Reconstitution	Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Transportation	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Kumar S, et al. Biochem. Biophys. Res. Commun. 185:1155-1161(1992). 2. Hatakeyama S, et al. J. Biol. Chem. 272:15085-15092(1997). 3. Carninci P, et al. Science 309:1559-1563(2005). 4. Ermekova K.S, et al. J. Biol. Chem. 272:32869-32877(1997). 5. Trinidad J.C, et al. Mol. Cell. Proteomics 5:914-922(2006).
Limitation	For research use only

PDF Data Sheet	- Click to download the Data Sheet
MSDS	- Click to download the Material Safety Data Sheet