TRPC1 antibody

Rabbit antibody to 2d extracellular loop of TRPC1: whole serum

$240USD

Code	OST00186W
ID Tag	Rb593-100808-WS
Ordering info	Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors. This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
Unit size	100 µl
Immunogen	A synthetic peptide from the 2d extracellular loop of human TRPC1 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and mouse. The location of the epitope is highlighted in green.
Conjugate	Unconjugated antibody
Accession	TRPC1_RAT TRPC1_MOUSE TRPC1_HUMAN
Also known as	Short transient receptor potential channel 1, TrpC1, TRP-1 protein, Trp1, Trrp1, Trpc1 transient receptor potential cation channel, subfamily C, member 1, Mtrp1, Trp-related protein 1
Background	FUNCTION: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. SUBUNIT: Interacts with TRPC3. Interacts with ITPR3. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Seems to be ubiquitous.
Host	NZ white rabbit
Purity	Whole serum
Clonality	Polyclonal
Isotype	Polyclonal, whole serum
Applications	IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity	Specific for TRPC1.
Spcs X-react.	Rat, mouse and human. Other species not yet tested.
Format	Lyophilised
Reconstitution	Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Transportation	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Wang W, et al. Am. J. Physiol. 276:C969-C979(1999). 2. Zhu X, et al. FEBS Lett. 373:193-198(1995). 3. Wes P.D, et al. Proc. Natl. Acad. Sci. U.S.A. 92:9652-9656(1995). 4. Zitt C, et al. Neuron 16:1189-1196(1996). 5. Lockwich T.P, et al. J. Biol. Chem. 275:11934-11942(2000).
Limitation	For research use only

IF (confocal) on rat trigeminal at 1 : 500 dilution using Rabbit antibody to 2d extracellular loop of TRPC1: whole serum (OST00186W), DAPI counterstained

IF (confocal) on rat brain at 1 : 500 dilution using Rabbit antibody to 2d extracellular loop of TRPC1: whole serum (OST00186W), DAPI counterstained appearing in blue.

IF (confocal) on rat olfactory bulb at 1 : 500 dilution using Rabbit antibody to 2d extracellular loop of TRPC1: whole serum (OST00186W), DAPI counterstained appearing in blue.

IF (confocal) on rat brain at 1 : 500 dilution using Rabbit antibody to 2d extracellular loop of TRPC1: whole serum (OST00186W), DAPI counterstained appearing in blue.

IF (confocal) on rat trigeminal at 1 : 500 dilution using Rabbit antibody to 2d extracellular loop of TRPC1: whole serum (OST00186W), DAPI counterstained appearing in blue.

PDF Data Sheet	- Click to download the Data Sheet
MSDS	- Click to download the Material Safety Data Sheet

Associated Products

Code	Product Name
GST00029P	TRPC1 control peptide
OST00286G	Rabbit antibody to 2d extracellular loop of TRPC1: IgG
OST00292W	Sheep antibody to 2d extracellular loop of TRPC1: whole serum