Code
OSN00035W
$240USD    Buy Now 

ID Tag
Rb1113-130909-WS

Immunogen
A synthetic peptide to extracellular domain of human Neuroligin-1 (NLGN1) conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in Neuroligin-2.

Accession

Also known as
NLGN1; NLGN2

Target
Function: Neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. Seems to play role in formation or maintenance of synaptic junctions. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses.
Subcellular location: Cell membrane; Single-pass type I membrane protein. Cell junction › synapse. Cell junction › synapse › postsynaptic cell membrane › postsynaptic density. Note: Enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Transportation
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Jamain S, et al. Nat. Genet. 34:27-29(2003)
2. Irie M, et al. Science 277:1511-1515(1997)
3. Scheiffele P, et al. Cell 101:657-669(2000)
4. Kikuno R, et al. DNA Res. 6:197-205(1999)
5. Ota T, et al. Nat. Genet. 36:40-45(2004)

Limitation
For research use only

Code
OSN00035W
$240USD    Buy Now 

Unit size
100 µl

Conjugate
Unconjugated antibody

Host
NZ white rabbit

Purity
Whole serum

Clonality
Polyclonal

Isotype
Polyclonal, whole serum

Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity
Specific for NLGN1 and NLGN2.

Spcs X-react.
Human, rat, mouse. Other species not yet tested.

Format
Lyophilised

Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Code
OSN00035W
$240USD    Buy Now 

Ordering
Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors.
This item is in our stock. The expected delivery time is within 5 business days worldwide.

Products

Rabbit antibody to extracellular domain of Neuroligin-1, 2: whole serum