| Code |
OSC00135W |
| ID Tag |
Rb855-290309-WS |
| Ordering info |
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This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
 |
| Unit size |
100 µl |
| Immunogen |
A synthetic peptide from extracellular domain of human CD36 (Fatty acid translocase) conjugated to an immunogenic carrier protein was used as the antigen. |
| Conjugate |
Unconjugated antibody |
| Accession |
CD36_HUMAN |
| Also known as |
Platelet glycoprotein 4, Platelet glycoprotein IV,GPIV, Glycoprotein IIIb, GPIIIB, Leukocyte differentiation antigen CD36, PAS IV, PAS-4, Platelet collagen receptor, Fatty acid translocase, FAT, Thrombospondin receptor, CD36, GP3B, GP4 |
| Background |
FUNCTION: Seems to have numerous potential physiological functions. Recent compelling evidence from rodent and human studies raise the possibility for an additional sixth taste modality devoted to the perception of lipids. Recent studies strongly suggest that lingual CD36, being implicated in the perception of dietary fat, may act as a gustatory lipid sensor (1).
Binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport.
Defects in CD36 are the cause of platelet glycoprotein IV deficiency; also known as CD36 deficiency. Platelet glycoprotein IV deficiency can be divided into 2 subgroups. The type I phenotype is characterized by platelets and monocytes/macrophages exhibiting complete CD36 deficiency. The type II phenotype lacks the surface expression of CD36 in platelets, but expression in monocytes/macrophages is near normal.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. |
| Host |
NZ white rabbit |
| Purity |
Whole serum |
| Clonality |
Polyclonal |
| Isotype |
Polyclonal, whole serum |
| Applications |
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Specificity |
Specific for CD36. |
| Spcs X-react. |
Human. Other species not yet tested. |
| Format |
Lyophilised |
| Reconstitution |
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage |
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Expiry Date |
12 months after reconstitution |
| Transportation |
This item will be shipped to you at ambient temperature in a lyophilised form. |
| References |
1. Khan NA, et al. Biochim Biophys Acta. 2009 Jan 14.
2. Taylor K.T, et al. Gene 133:205-212(1993)
3. Wyler B, et al. Thromb. Haemost. 70:500-505(1993)
4. Armesilla A.L, et al. J. Biol. Chem. 269:18985-18991(1994)
5. Hanawa H, et al. J. Med. Genet. 39:286-291(2002)
6. Oquendo P, et al. Cell 58:95-101(1989) |
| Limitation |
For research use only |
Primary Antibodies 
