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Rabbit antibody to 2d cytoplasmic loop of human transmembrane channel-like protein 6 (TMC6, EVER1, Protein LAK-4, EVIN1): whole serum

$240USD  

Code OST00103W
ID Tag Rb485-290608-WS
Ordering info Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors.
This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
Unit size 100 µl
Immunogen A synthetic peptide from the 2d cytoplasmic loop of human transmembrane channel-like protein 6 (TMC6, EVER1, Protein LAK-4, EVIN1) conjugated to an immunogenic carrier protein was used as the immunogen.
Conjugate Unconjugated antibody
Accession TMC6_HUMAN
Also known as TMC6, EVER1, Epidermodysplasia verruciformis protein 1, Protein LAK-4, EVIN1
Background SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Expressed in placenta, prostate, testis, activated T-lymphocytes and lymphokine-activated killer (LAK) lymphocytes.
DISEASE: Defects in TMC6 are a cause of epidermodysplasia verruciformis. It is a rare autosomal recessive genodermatosis associated with a high risk of skin carcinoma that results from an abnormal susceptibility to infection by specific human papillomaviruses. Infection leads to persistent wart-like or macular lesions.
Host NZ white rabbit
Purity Whole serum
Clonality Polyclonal
Isotype Polyclonal, whole serum
Applications IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity Specific for TMC6.
Spcs X-react. Human. Other species not yet tested.
Format Lyophilised
Reconstitution Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Storage Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months after reconstitution
Transportation This item will be shipped to you at ambient temperature in a lyophilised form.
References 1. Ramoz N, et al. Nat. Genet. 32:579-581(2002).
2. Kurima K, et al. Genomics 82:300-308(2003).
3. Ota T, et al. Nat. Genet. 36:40-45(2004).
4. Tate G, et al. J. Hum. Genet. 49:223-225(2004).
5. Olsen J.V, et al. Cell 127:635-648(2006).
Limitation For research use only
PDF Data Sheet

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MSDS

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Associated Products
 
Code Product Name
OST00155W Rabbit antibody to 1t lumenal part of human transmembrane channel-like protein 6 (TMC6, EVER1, Protein LAK-4, EVIN1): whole serum
 
 
   

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