OA1 antibody, GPR143 antibody

Rabbit antibody to OA1

$240USD

Code	OSO00003W
ID Tag	Rb757-140209-WS
Ordering info	Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors. This item is in our stock. The expected delivery time is within 5 business days worldwide.
Unit size	100 µl
Immunogen	A synthetic peptide from the 4th cytoplasmic domain of human ocular albinism type 1 protein (G protein-coupled receptor 143 or GPR143, OA1) conjugated to an immunogenic carrier protein was used as the immunogen.
Conjugate	Unconjugated antibody
Accession	GPR143_HUMAN
Also known as	G-protein coupled receptor 143, ocular albinism type 1 protein, GPR143, OA1
Target	Ocular albinism type 1 protein is a conserved integral membrane protein with seven transmembrane domains. It is expressed in the eye and epidermal melanocytes. FUNCTION: Not known; binds heterotrimeric G proteins. SUBCELLULAR LOCATION: Melanosome membrane; Multi-pass membrane protein. Note: Targeted to intracellular organelles, namely the melanosomes in pigment cells. TISSUE SPECIFICITY: Exclusively expressed in pigment cells. DISEASE: Defects in GPR143 are the cause of ocular albinism type 1 (OA1); also known as Nettleship-Falls type ocular albinism. OA1 is an X-linked disorder characterized by severe impairment of visual acuity, retinal hypopigmentation and the presence of macromelanosomes.
Host	NZ white rabbit
Purity	Whole serum
Clonality	Polyclonal
Isotype	Polyclonal, whole serum
Applications	IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity	Specific for OA1.
Spcs X-react.	Human. Other species not yet tested.
Format	Lyophilised
Reconstitution	Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Transportation	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Bassi M.T, et al. Nat. Genet. 10:13-19(1995). 2. Oetting W.S, et al. Hum. Mutat. 13:99-115(1999). 3. Basrur V, et al. J. Proteome Res. 2:69-79(2003). 4. Chi A, et al. J. Proteome Res. 5:3135-3144(2006). 5. Schiaffino M.V, et al. Hum. Mol. Genet. 4:2319-2325(1995).
Limitation	For research use only

PDF Data Sheet	- Click to download the Data Sheet
MSDS	- Click to download the Material Safety Data Sheet

Associated Products

Code	Product Name
OSO00004G	Rabbit antibody to OA1