|
|
|
|
Code
OST00169W
$240USD
ID Tag
Rb985-280609-WS
Immunogen
A synthetic peptide from the 1t cytoplasmic domain of rat TRPA1 (ANKTM1) conjugated to an immunogenic carrier protein was used as the antigen.
The location of the epitope is highlighted in green.
The location of the epitope is highlighted in green.
Accession
Also known as
Transient receptor potential cation channel subfamily A member 1, ankyrin-like with transmembrane domains protein 1, transformation sensitive protein p120, ANKTM1
Target
The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control.
TISSUE SPECIFICITY: Expressed in inner ear. In inner ear, it is found in the distal half of stereocilia, along the length of the kinocilium and at high level in the pericuticular zone (at protein level). Specifically expressed in a subset of nociceptive neurons. Expressed in the same neurons that TRPV1. In contrast, it is not expressed in neurons expressing TRPM8. Expressed in the superior cervical ganglion.
DEVELOPMENTAL STAGE: During utricle development, it is first expressed at E15 and E16 and peaks at E17. It drops at E18 but increases again at E19, possibly corresponding to a second wave of hair cells that are generated at E15.
Inhibited by ruthenium red, a potent blocker of TRPV channels.
TISSUE SPECIFICITY: Expressed in inner ear. In inner ear, it is found in the distal half of stereocilia, along the length of the kinocilium and at high level in the pericuticular zone (at protein level). Specifically expressed in a subset of nociceptive neurons. Expressed in the same neurons that TRPV1. In contrast, it is not expressed in neurons expressing TRPM8. Expressed in the superior cervical ganglion.
DEVELOPMENTAL STAGE: During utricle development, it is first expressed at E15 and E16 and peaks at E17. It drops at E18 but increases again at E19, possibly corresponding to a second wave of hair cells that are generated at E15.
Inhibited by ruthenium red, a potent blocker of TRPV channels.
Isotype
Polyclonal, whole serum
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Transportation
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Jordt S.-E, et al. Nature 427:260-265(2004).
2. Story G.M, et al. Cell 112:819-829(2003).
2. Story G.M, et al. Cell 112:819-829(2003).
Limitation
For research use only
Code
OST00169W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for TRPA1.
Spcs X-react.
Rat. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Transportation
This item will be shipped to you at ambient temperature in a lyophilised form.
Code
OST00169W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OST00169W
$240USD
Ordering
Order online using the shopping cart ("Add to Cooler"), by email to
sales@osenses.com
or fax to 61-8-827 0 8586 and pay via PayPal by
MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors.
This item is in our stock. The expected delivery time is within 5 business days worldwide.
This item is in our stock. The expected delivery time is within 5 business days worldwide.
Products
| Rabbit antibody to TRPA1 |
