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Code
OSP00073W
$240USD
ID Tag
Rb990-280609-WS
Immunogen
A synthetic peptide from the cytoplasmic domain of human KCNE3 (Potassium voltage-gated channel subfamily E member 3) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known as
Potassium voltage-gated channel subfamily E member 3, Minimum potassium ion channel-related peptide 2, Potassium channel subunit beta MiRP2, MinK-related peptide 2
Target
Function: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion.
Tissue specificity: Widely expressed with highest levels in kidney and moderate levels in small intestine.
Subcellular location: Membrane; Single-pass type I membrane protein.
Tissue specificity: Widely expressed with highest levels in kidney and moderate levels in small intestine.
Subcellular location: Membrane; Single-pass type I membrane protein.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Transportation
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Melman Y.F, et al. J. Biol. Chem. 276:6439-6444(2001)
2. Schroeder B.C, et al. Nature 403:196-199(2000)
3. Abbott G.W, et al. Cell 104:217-231(2001)
4. Dias Da Silva M.R, et al. J. Clin. Endocrinol. Metab. 87:4881-4884(2002)
5. Ohno S, et al. Hum. Mutat. 30:557-563(2009)
2. Schroeder B.C, et al. Nature 403:196-199(2000)
3. Abbott G.W, et al. Cell 104:217-231(2001)
4. Dias Da Silva M.R, et al. J. Clin. Endocrinol. Metab. 87:4881-4884(2002)
5. Ohno S, et al. Hum. Mutat. 30:557-563(2009)
Limitation
For research use only
Code
OSP00073W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for KCNE3.
Spcs X-react.
Human, rat, mouse. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Code
OSP00073W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OSP00073W
$240USD
Ordering
Order online using the shopping cart ("Add to Cooler"), by email to
sales@osenses.com
or fax to 61-8-827 0 8586 and pay via PayPal by
MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors.
This item is in our stock. The expected delivery time is within 5 business days worldwide.
This item is in our stock. The expected delivery time is within 5 business days worldwide.
Products
Rabbit antibody to cytoplasmic domain of KCNE3: whole serum
