A synthetic peptide from the 1t cytoplasmic domain of human Caveolin-1 (CAV1, CAV) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in many other species including rat, mouse.
Also known as
FUNCTION: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
SUBCELLULAR LOCATION: Golgi apparatus membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein. Note: Potential hairpin-like structure in the membrane. Membrane protein of protein of caveolae.
TISSUE SPECIFICITY: In muscle and lung, less so in liver, brain and kidney.
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
12 months after reconstitution
This item will be shipped to you at ambient temperature in a lyophilised form.
1. Aboulaich N, et al. Biochem. J. 383:237-248(2004).
2. Eberle H.B, et al. J. Cell Sci. 115:827-838(2002).
3. Olsen J.V, et al. Cell 127:635-648(2006).
4. Schilling K, et al. Mol. Biol. Cell 17:3870-3880(2006).
5. Dephoure N, et al. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
For research use only
NZ white rabbit
Polyclonal, whole serum
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.
Specific for Caveolin-1.
Mouse, rat, human. Other species not yet tested.
Reconstitute in 150 µl of sterile water. Centrifuge to remove any insoluble material.