| |- Cancer
| |- Toxins
| `- Vision

Code
OSR00088W
$240USD    Buy Now 

ID Tag
Rb91-281007-WS

Immunogen
A synthetic peptide from aa region 1100-1150 of mouse TRPM4 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat.

Accession

Also known
Transient receptor potential cation channel subfamily M member 4, Long transient receptor potential channel 4, Calcium-activated non-selective cation channel 1, Melastatin-like 2, MLS2s

Target
FUNCTION: Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) > K(+) > Cs(+) > Li(+)), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Gibbs R.A, et al. Nature 428:493-521(2004).

Limitation
For research use only

Related
products

Code
OSR00088W
$240USD    Buy Now 

Unit size
100 l

Conjugate
Unconjugated antibody

Host
NZ white rabbit

Purity
Whole serum

Clonality
Polyclonal

Isotype
Polyclonal, whole serum

Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity
Specific for TRPM4.

Spcs X-react.
Mouse, rat. Other species not yet tested.

Format
Lyophilised

Reconstitution
Reconstitute in 100 l of sterile water. Centrifuge to remove any insoluble material.

Code
GST00013P
$120USD   

ID Tag
563561-14

Unit size
50 g

Accession

Also known
Transient receptor potential cation channel subfamily M member 4, Long transient receptor potential channel 4, Calcium-activated non-selective cation channel 1, Melastatin-like 2, MLS2s

Target
This is the immunising peptide for the product Rabbit antibody to TRPM4 (OSR00088W) and Sheep antibody to TRPM4 (OST00027W)

Purity
>81%

Applications
Control peptide

Format
Lyophilised

Reconstitution
This peptide is soluble in PBS and water.

Storage
Maintain refrigerated at 2-8C for up to 12 months. After reconstitution keep at -20C. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

Limitation
For research use only

Related Products
OSR00088W,OST00027W

Code
OSR00088W
$240USD    Buy Now 


Rabbit antibody to TRPM4 (1100-1150) IHC on rat spinal cord (paraffin section) using Rabbit antibody to TRPM4 (OSR00088W) at 1: 300 dilution incubated overnight at 4C.
Rabbit antibody to TRPM4 (1100-1150) IHC on rat spinal cord (paraffin section) using Rabbit antibody to TRPM4 (1100-1150) (OSR00088W) at 1: 300 dilution incubated overnight at 4C.
Rabbit antibody to TRPM4 (1100-1150) IHC on rat spinal cord (paraffin section) using Rabbit antibody to TRPM4 (1100-1150) (OSR00088W) at 1: 300 dilution incubated overnight at 4C.
Rabbit antibody to TRPM4 (1100-1150) IHC on rat spinal cord (paraffin section) using Rabbit antibody to TRPM4 (1100-1150) (OSR00088W) at 1: 300 dilution incubated overnight at 4C.
Rabbit antibody to TRPM4 (1100-1150) IHC on rat spinal cord (paraffin section) using Rabbit antibody to TRPM4 (1100-1150) (OSR00088W) at 1: 300 dilution incubated overnight at 4C.
Rabbit antibody to TRPM4 (1100-1150) IHC on rat spinal cord (paraffin section) using Rabbit antibody to TRPM4 (1100-1150) (OSR00088W) at 1: 300 dilution incubated overnight at 4C.
Rabbit antibody to TRPM4 (1100-1150) IHC on rat spinal cord (paraffin section) using Rabbit antibody to TRPM4 (1100-1150) (OSR00088W) at 1: 300 dilution incubated overnight at 4C.
Rabbit antibody to TRPM4 (1100-1150) IHC on rat spinal cord (paraffin section) using Rabbit antibody to TRPM4 (1100-1150) (OSR00088W) at 1: 300 dilution incubated overnight at 4C.
Rabbit antibody to TRPM4 (1100-1150) IHC on rat spinal cord (paraffin section) using Rabbit antibody to TRPM4 (1100-1150) (OSR00088W) at 1: 300 dilution incubated overnight at 4C.
Rabbit antibody to TRPM4 (1100-1150) IHC on rat spinal cord (paraffin section) using Rabbit antibody to TRPM4 (1100-1150) (OSR00088W) at 1: 300 dilution incubated overnight at 4C.
Rabbit antibody to TRPM4 (1100-1150) IHC on rat spinal cord (paraffin section) using Rabbit antibody to TRPM4 (1100-1150) (OSR00088W) at 1: 300 dilution incubated overnight at 4C.
Rabbit antibody to TRPM4 (1100-1150) IHC on rat spinal cord (paraffin section) using Rabbit antibody to TRPM4 (1100-1150) (OSR00088W) at 1: 300 dilution incubated overnight at 4C.
Rabbit antibody to TRPM4 (1100-1150) IHC on rat spinal cord (paraffin section) using Rabbit antibody to TRPM4 (1100-1150) (OSR00088W) at 1: 300 dilution incubated overnight at 4C.
Rabbit antibody to TRPM4 (1100-1150) IHC on rat spinal cord (paraffin section) using Rabbit antibody to TRPM4 (1100-1150) (OSR00088W) at 1: 300 dilution incubated overnight at 4C.
Rabbit antibody to TRPM4 (1100-1150) IHC on rat spinal cord (paraffin section) using Rabbit antibody to TRPM4 (1100-1150) (OSR00088W) at 1: 300 dilution incubated overnight at 4C.
Rabbit antibody to TRPM4 (1100-1150) WB on rat spinal cord lysate using Rabbit antibody to TRPM4 (1100-1150) (OSR00088W) at 1:500 dilution. Incubated 30 min at RT with shake. Blocking: 0.5% LFDM in 1x PBS containing 0.1% Tween-20
Products
Rabbit antibody to TRPM4 (1100-1150)
Content

Download Protocols

IHC, Paraffin section
APES coating of slides
Content

Watch Videos

Autoperfuser OS2100
Red Carpet: A Histology Carpet for Slides