Code
OSR00359W
$240USD    Buy Now 

ID Tag
Rb1360-140310-WS

Immunogen
A synthetic peptide to from c-terminal region of mouse Robo1 (Roundabout homolog 1) conjugated to an immunogenic carrier protein was used as the antigen.

Accession

Also known as
Roundabout homolog 1, Dutt1

Target
FUNCTION: Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development.
Subcellular location: Membrane; Single-pass type I membrane protein
Tissue specificity: Expressed in embryonal spinal chord. Expressed in embryonal lung, and in adult lung bronchial epithelial cells of large proximal airways.

Isotype
Polyclonal, whole serum

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Transportation
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Xian J, et al. Proc. Natl. Acad. Sci. U.S.A. 98:15062-15066(2001)
2. Long H, et al. Neuron 42:213-223(2004)
3. Sundaresan V, et al. Mol. Cell. Neurosci. 11:29-35(1998)
4. Yuan W, et al. Dev. Biol. 212:290-306(1999)
5. Yuasa-Kawada J, et al. Proc. Natl. Acad. Sci. U.S.A. 106:14530-14535(2009)

Limitation
For research use only

Code
OSR00359W
$240USD    Buy Now 

Unit size
100 µl

Conjugate
Unconjugated antibody

Host
NZ white rabbit

Purity
Whole serum

Clonality
Polyclonal

Isotype
Polyclonal, whole serum

Applications
IHC, WB. A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity
Specific for Robo1.

Spcs X-react.
Mouse. Other species not yet tested.

Format
Lyophilised

Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Transportation
This item will be shipped to you at ambient temperature in a lyophilised form.

Code
OSR00359W
$240USD    Buy Now 

Ordering
Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors.
This item is in our stock. The expected delivery time is within 5 business days worldwide.

Products

Rabbit antibody to Robo1