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Rabbit antibody to c-terminal region of human Glucose transporter type 10 (GLUT10, SLC2A10): whole serum

$240USD  

Code OSG00048W
ID Tag Rb1072-020809-WS
Ordering info Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors.
This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
Unit size 100 µl
Immunogen A synthetic peptide from c-terminal region of human Glucose transporter type 10 (GLUT10) conjugated to an immunogenic carrier protein was used as the antigen.
Conjugate Unconjugated antibody
Accession GTR10_HUMAN
Also known as GTR10, Solute carrier family 2, facilitated glucose transporter member 10, GLUT-10, SLC2A10, GLUT10
Background FUNCTION: Facilitative glucose transporter.
SUBCELLULAR LOCATION: Endomembrane system; Multi-pass membrane protein. Cytoplasm › perinuclear region.
TISSUE SPECIFICITY:
Widely expressed; highest levels in liver and pancreas.
Involvement in disease: Defects in SLC2A10 are the cause of arterial tortuosity syndrome (ATS). ATS is an autosomal recessive disorder characterized by tortuosity and elongation of major arteries, often resulting in death at young age. Other typical features include aneurysms of large arteries and stenosis of the pulmonary artery, in association with facial features and several connective tissue manifestations such as soft skin and joint laxity. Histopathological findings include fragmentation of elastic fibers in the tunica media of large arteries.
Host NZ white rabbit
Purity Whole serum
Clonality Polyclonal
Isotype Polyclonal, whole serum
Applications IHC. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity Specific for GLUT-10.
Spcs X-react. Human. Other species not yet tested.
Format Lyophilised
Reconstitution Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Storage Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months after reconstitution
Transportation This item will be shipped to you at ambient temperature in a lyophilised form.
References 1. McVie-Wylie A.J, et al. Genomics 72:113-117(2001)
2. Dawson P.A, et al. Mol. Genet. Metab. 74:186-199(2001)
3. Ota T, et al. Nat. Genet. 36:40-45(2004)
4. Deloukas P, et al. Nature 414:865-871(2001)
5. Callewaert B.L, et al. Hum. Mutat. 29:150-158(2008)
Limitation For research use only
PDF Data Sheet

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MSDS

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