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Code
OSC00172W
$240USD
ID Tag
Rb1046-020809-WS
Immunogen
A synthetic peptide from the c-terminal region of human CNG channel alpha-4 (CNG4, CNGA4) conjugated to an immunogenic carrier protein was used as the antigen.
Accession
Also known as
CNGA4, cGMP-gated cation channel alpha-4, CNG-4, CNG4, Cyclic nucleotide-gated channel alpha-4, Cyclic nucleotide-gated channel, photoreceptor, Cyclic nucleotide gated cation channel 3, Cone photoreceptor cGMP-gated channel subunit alpha, CNCG4, CNG 4
Target
FUNCTION: Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Transportation
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Ota T, et al. Nat. Genet. 36:40-45(2004)
2. Taylor T.D, et al. Nature 440:497-500(2006)
3. Bradley J, et al. Nat. Neurosci. 7:705-710(2004)
4. Brady J.D, et al. Proc. Natl. Acad. Sci. U.S.A. 103:15635-15640(2006)
2. Taylor T.D, et al. Nature 440:497-500(2006)
3. Bradley J, et al. Nat. Neurosci. 7:705-710(2004)
4. Brady J.D, et al. Proc. Natl. Acad. Sci. U.S.A. 103:15635-15640(2006)
Limitation
For research use only
Code
OSC00172W
$240USD
Unit size
100 µl
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal
Isotype
Polyclonal, whole serum
Applications
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for CNGA4.
Spcs X-react.
Human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Code
OSC00172W
$240USD
PDF Data Sheet
- Click to download the Data SheetMSDS
Code
OSC00172W
$240USD
Ordering
Order online using the shopping cart ("Add to Cooler"), by email to
sales@osenses.com
or fax to 61-8-827 0 8586 and pay via PayPal by
MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors.
This item is in our stock. The expected delivery time is within 5 business days worldwide.
This item is in our stock. The expected delivery time is within 5 business days worldwide.
Products
Rabbit antibody to c-terminal region of human CNG channel alpha-4 (CNG4, CNGA4): whole serum
