EDNRB antibody, Endothelin B receptor antibody

A synthetic peptide from the c-terminal of human Endothelin B receptor (EDNRB) conjugated to an immunogenic carrier protein was used as the immunogen. The peptide is homologous in rat and mouse.

Accession

EDNRB_HUMAN
EDNRB_RAT
EDNRB_MOUSE

Also known as

Endothelin receptor non-selective type, EDNRB, ETRB

Target

FUNCTION: Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: Expressed in placental stem villi vessels, but not in cultured placental villi smooth muscle cells.

Isotype

Polyclonal, IgG

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Transportation

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Nakamuta M, et al. Biochem. Biophys. Res. Commun. 177:34-39(1991)
2. Arai H, et al. Jpn. Circ. J. 56:1303-1307(1992)
3. Elshourbagy N.A, et al. J. Biol. Chem. 268:3873-3879(1993)
4. Tsutsumi M, et al. Gene 228:43-49(1999)
5. Pingault V, et al. Hum. Genet. 111:198-206(2002)

Limitation

For research use only

Associated
products

Code	Product Name
OSE00021W	Rabbit antibody to EDNRB

Code

OSE00022G

$240USD

Unit size

500 µg

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

IgG

Clonality

Polyclonal

Isotype

Polyclonal, IgG

Applications

IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for EDNRB.

Spcs X-react.

Human, rat, mouse. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Transportation

This item will be shipped to you at ambient temperature in a lyophilised form.

Code

OSE00022G

$240USD

PDF Data Sheet	- Click to download the Data Sheet
MSDS	- Click to download the Material Safety Data Sheet

Code

OSE00022G

$240USD

Ordering info Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors.
This item is in our stock. The expected delivery time is within 5 business days worldwide.

Products

Rabbit antibody to Endothelin B receptor

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