Rabbit antibody to rat contactin-5 (NB-2, contactin 5, CNTN5): whole serum

$240USD

Code	OSC00021W
ID Tag	Rb359-200308-WS
Ordering info	Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors. This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
Unit size	100 µl
Immunogen	A synthetic peptide as a part of rat contactin-5 (NB-2, contactin 5, CNTN5) conjugated to an immunogenic carrier protein was used as the immunogen.
Conjugate	Unconjugated antibody
Accession	CNTN5_RAT
Also known as	NB-2, contactin 5, CNTN5, Neural recognition molecule NB-2
Background	The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. FUNCTION: Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system. SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor. TISSUE SPECIFICITY: Specifically expressed in the nervous system. Expressed in cerebrum and cerebellum but at low level in spinal chord. In brain, it is expressed in highly restricted regions at postnatal day 7, such as the auditory pathway, including the cochlear nucleus, superior olive, inferior colliculus, medial geniculate nucleus and auditory cortex. Expressed in the accessory olfactory bulb, glomerular and mitral cell layers in the olfactory bulb, anterior thalamic nuclei, layers II-IV of the cerebral cortex, dentate gyrus of the hippocampus and external granule cells and Purkinje cells of the cerebellum. Also expressed in the piriform cortex, inferior olive and facial nucleus. Weakly or not expressed in other parts of the brain. DEVELOPMENTAL STAGE: Expressed after birth, reaching a maximum at postnatal day 14 in the cerebrum and postnatal day 3 in the cerebellum. Then, it decreases abruptly thereafter (at protein level).
Host	NZ white rabbit
Purity	Whole serum
Clonality	Polyclonal
Isotype	Polyclonal, whole serum
Applications	IHC, WB. A dilution of 1 : 300 to 1 : 3000 is recommended. The optimal dilution should be determined by the end user.
Specificity	Specific for contactin-5.
Spcs X-react.	Rat. Other species not yet tested.
Format	Lyophilised
Reconstitution	Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Transportation	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Ogawa J, et al. J. Neurosci. Res. 65:100-110(2001).
Limitation	For research use only

PDF Data Sheet	- Click to download the Data Sheet
MSDS	- Click to download the Material Safety Data Sheet

Associated Products

Code	Product Name
OSC00015W	Rabbit antibody to human contactin-5 (NB-2, hNB-2, HNB-2s, contactin 5, CNTN5): whole serum
OSC00019W	Rabbit antibody to mouse Contactin-5 (NB-2, contactin 5, CNTN5): whole serum