| Code |
OSC00186W |
| ID Tag |
Rb1189-260909-WS |
| Ordering info |
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This item is in our stock. The expected delivery time is within 5 business days worldwide.
 |
| Unit size |
100 µl |
| Immunogen |
A synthetic peptide from 2d cytoplasmic domain of human Connexin-46 (CX46, CXA3) conjugated to an immunogenic carrier protein was used as the antigen. |
| Conjugate |
Unconjugated antibody |
| Accession |
CX46_HUMAN |
| Also known as |
CXA3, Gap junction alpha-3 protein, Connexin-46, Connexin 46, Connexin46, GJA3 |
| Target |
FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Tissue specificity: Low levels were detected in skin, heart, kidney, testis, ovary, intestine. Expression not detected in brain, sciatic nerve or liver.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Cell junction › gap junction. |
| Host |
NZ white rabbit |
| Purity |
Whole serum |
| Clonality |
Polyclonal |
| Isotype |
Polyclonal, whole serum |
| Applications |
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Specificity |
Specific for Connexin-46. |
| Spcs X-react. |
Human. Other species not yet tested. |
| Format |
Lyophilised |
| Reconstitution |
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material. |
| Storage |
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Expiry Date |
12 months after reconstitution |
| Transportation |
This item will be shipped to you at ambient temperature in a lyophilised form. |
| References |
1. Mackay D, et al. Am. J. Hum. Genet. 64:1357-1364(1999)
2. Dunham A, et al. Nature 428:522-528(2004)
3. Rees M.I, et al. Hum. Genet. 106:206-209(2000)
4. Jiang H, et al. Mol. Vis. 9:579-583(2003)
5. Hansen L, et al. Mol. Vis. 12:1033-1039(2006) |
| Limitation |
For research use only |
Primary Antibodies 
