Code
OSC00255W
$240USD
ID Tag
Rb1769-260312-WS
Immunogen
A synthetic peptide from aa region 2-50 of mouse cFos protein conjugated to an immunogenic carrier protein has been used as the antigen.
Accession
Also known as
Proto-oncogene protein cFOS, c-Fos
Target
FUNCTION: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
SUBUNIT: Heterodimer. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA. Interacts with MAFB
SUBCELLULAR LOCATION: Nucleus.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after purchase
Transportation
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Hai T, et al. Genes Dev. 3:2083-2090(1989).
2. Heilig R, et al. Nature 421:601-607(2003).
3. Roux P, et al. Oncogene 6:2155-2160(1991).
Limitation
For research use only
Associated
products
Code
OSC00255W
$240USD
Unit size
100 µl
Purity
Whole serum
Conjugate
Unconjugated antibody
Host
NZ white rabbit
Purity
Whole serum
Clonality
Polyclonal antibody
Isotype
Polyclonal, whole serum
Applications
IHC, WB. Use at a dilution of 1 : 300 to 1 : 2000. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity
Specific for cFOS.
Spcs X-react.
Rat, mouse, human. Other species not yet tested.
Format
Lyophilised
Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.