A synthetic peptide from human Cathelicidin antimicrobial peptide (CAP-18, hCAP-18, antibacterial protein LL-37, CAMP, CRAMP, FALL39) conjugated to an immunogenic carrier protein has been used as the immunogen.
The location of the epitope is highlighted in
Also known as
CAMP, CAP18, FALL39, FALL-39, 18 kDa cationic antimicrobial protein, CAP-18, hCAP-18, LL37, CRAMP, HSD26
Cathelicidin antimicrobial protein is an antimicrobial protein found in specific granules of polymorphonuclear leukocytes.
FUNCTION: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Expressed in bone marrow and testis and neutrophils.
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
12 months after reconstitution
This item will be shipped to you at ambient temperature in a lyophilised form.
1. Agerberth B, et al. Proc. Natl. Acad. Sci. U.S.A. 92:195-199(1995).
2. Cowland J.B, et al. FEBS Lett. 368:173-176(1995).
3. Larrick J.W, et al. Infect. Immun. 63:1291-1297(1995).
4. Larrick J.W, et al. FEBS Lett. 398:74-80(1996).
5. Gudmundsson G.H, et al. Eur. J. Biochem. 238:325-332(1996).
6. Bals R, et al. Clin. Diagn. Lab. Immunol. 8:370-375(2001).
For research use only
Clone OSX12, monoclonal
IHC, IF, WB, flow cytometry. Use at a concentration of 5-10 µg/ml. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Specific for Cathelicidin antimicrobial peptide.
Human, other species not yet tested.
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.