TAS1R3 antibody, TR3 antibody

Goat antibody to 1t extracellular loop of mouse taste receptor, type 1, member 3 (Tas1r3, TS1R3): whole serum

$240USD

Code	OST00319W
ID Tag	Gt209-241009-WS
Ordering info	Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors. This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
Unit size	100 µl
Immunogen	A synthetic peptide from the 1t extracellular loop of mouse taste receptor, type 1, member 3 (Tas1r3, T1r3, Sac, Tr3, TS1R3) conjugated to an immunogenic carrier protein was used as the antigen.
Conjugate	Unconjugated antibody
Accession	TAS1R3_MOUSE
Also known as	Taste receptor type 1 member 3 (precursor), sweet taste receptor T1R3, saccharin preference protein, Sac, T1r3, Tr3, Tas1r3, TS1R3
Background	FUNCTION: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate) and also to most of the 20 standard L-amino acids, but not to their D-enantiomers or other compounds. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. SUBUNIT: Forms homodimers or heterodimers with TAS1R1 and TAS1R2. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in circumvallate, foliate and fungiform taste papillae as well as in taste buds on the palate. Also expressed in testis. Not expressed in brain, heart, kidney, liver or spleen. The topographic distribution in various taste papillae is different from those of other T1R members.
Host	Goat
Purity	Whole serum
Clonality	Polyclonal
Isotype	Polyclonal, whole serum
Applications	IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity	Specific for TAS1R3.
Spcs X-react.	Mouse. Other species not yet tested.
Format	Lyophilised
Reconstitution	Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Transportation	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Kitagawa M, et al. Biochem. Biophys. Res. Commun. 283:236-242(2001). 2. Bachmanov A.A, et al. Chem. Senses 26:925-933(2001). 3. Nelson G, et al. Cell 106:381-390(2001). 4. Sainz E, et al. J. Neurochem. 77:896-903(2001). 5. Li X, et al. Mamm. Genome 13:5-19(2002). 6. Ariyasu T, et al. In Vitro Cell. Dev. Biol. Anim. 39:80-88(2003).
Limitation	For research use only

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