Toll-like receptor 9 antibody, TLR9 antibody, CD289 antibody

Goat antibody to cytoplasmic domain of human TLR9 (Toll-like receptor 9): whole serum

$240USD

Code	OST00315W
ID Tag	Gt187-270909-WS
Ordering info	Order online using the shopping cart ("Add to Cooler"), by email to sales@osenses.com or fax to 61-8-827 0 8586 and pay via PayPal by MasterCard or Visa. You can also provide us with your Purchase Order Number (PON) and pay by check or wire transfer. Alternatively contact our distributors. This item is in our stock. The handling & shipping cost is $48 USD and the expected delivery time is within 5 business days worldwide.
Unit size	100 µl
Immunogen	A synthetic peptide from the cytoplasmic domain of human TLR9 (Toll-like receptor 9) conjugated to an immunogenic carrier protein was used as the antigen.
Conjugate	Unconjugated antibody
Accession	TLR9_HUMAN
Also known as	Toll-like receptor 9
Background	FUNCTION: Participates in the innate immune response to microbial agents. Detects the unmethylated cytidine-phosphate-guanosine (CpG) motifs present in bacterial DNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein. TISSUE SPECIFICITY: Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre-dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver.
Host	Goat
Purity	Whole serum
Clonality	Polyclonal
Isotype	Polyclonal, whole serum
Applications	IHC, WB, Flow Cyt. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specificity	Specific for TLR9.
Spcs X-react.	Human. Other species not yet tested.
Format	Lyophilised
Reconstitution	Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Transportation	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Du X, et al. Eur. Cytokine Netw. 11:362-371(2000) 2. Hemmi H, et al. Nature 408:740-745(2000) 3. Nakajima T, et al. Immunogenetics 60:727-735(2008) 4. Clark H.F, et al. Genome Res. 13:2265-2270(2003) 5. Sjoeblom T, et al. Science 314:268-274(2006)
Limitation	For research use only

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Associated Products

Code	Product Name
OST00299G	Rabbit antibody to cytoplasmic domain of human TLR9 (Toll-like receptor 9): IgG
OST00297W	Rabbit antibody to cytoplasmic domain of human TLR9 (Toll-like receptor 9): whole serum