A synthetic peptide from human SCP1 conjugated to blue carrier protein was used as the antigen.
Synaptonemal complex protein 1, SCP-1, Cancer/testis antigen 8, CT8
Function: Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for normal assembly of the central element of the synaptonemal complexes. Required for normal centromere pairing during meiosis. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility.
SUBCELLULAR LOCATION: Central element; chromosome, centromeric region; male germ cell nucleus; synaptonemal complex; transverse filament
Tissue specificity: Testis
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
12 months after reconstitution
This item will be shipped to you at ambient temperature in a lyophilised form.
1. Meuwissen R.L.J, et al. Genomics 39:377-384(1997)
For research use only
NZ white rabbit
Polyclonal, whole serum
IHC, WB. A dilution of 1: 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specific for SCP1.
Human. Other species not yet tested.
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.