A synthetic peptide from aa region 600-650 of human CACNA2D1 conjugated to blur carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
Voltage-dependent calcium channel subunit alpha-2/delta-1, Voltage-gated calcium channel subunit alpha-2/delta-1, CACNL2A, CCHL2A, MHS3
FUNCTION: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling.
Subcellular location: Membrane; Single-pass type I membrane protein
Tissue specificity: Central nervous system, skeletal muscle and aorta tissues.
Miscellaneous: Binds gabapentin, an antiepileptic drug.
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
12 months after reconstitution
This item will be shipped to you at ambient temperature in a lyophilised form.
1. Williams M.E, et al. Neuron 8:71-84(1992)
2. Liu T, et al. J. Proteome Res. 4:2070-2080(2005)
For research use only
NZ white rabbit
Polyclonal, whole serum
IHC, WB. A dilution of 1: 1000 to 1: 3000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specific for CACNA2D1.
Human, mouse, rat. Other species not yet tested.
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.