Tyrosine Hydroxylase antibody, TH antibody

Primary Antibodies

ABC Transporters

Autophagy

Cancer

Cellular

Immunology

Reporter Genes & Tags

Reproduction

SLC & Regulators

Subcellular Markers

Toxins

Peptides

Histology / Detection

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OVERVIEW
SPECS
CONTROL PEPTIDE
MSDS/DS
IMAGES

Code

OST00323W

$260USD

ID Tag

Rb1221-051209-WS

Immunogen

A synthetic peptide from aa region 30-100 of human Tyrosine Hydroxylase conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.

Accession

TH_HUMAN
TH_RAT
TH_MOUSE

Also known

TY3H, Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase, Tyrosine 3 hydroxylase, TH

Target

Function: Plays an important role in the physiology of adrenergic neurons.
Defects in TH are the cause of dystonia DOPA-responsive autosomal recessive (ARDRD); also known as autosomal recessive Segawa syndrome. ARDRD is a form of DOPA-responsive dystonia presenting in infancy or early childhood. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Some cases of ARDRD present with parkinsonian symptoms in infancy. Unlike all other forms of dystonia, it is an eminently treatable condition, due to a favorable response to L-DOPA.
Subcellular location: Nucleus. Cytoplasm
Tissue specificity: Mainly expressed in the brain and adrenal glands.

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date

12 months after reconstitution

Shipping

This item will be shipped to you at ambient temperature in a lyophilised form.

References

1. Kaneda N, et al. Biochem. Biophys. Res. Commun. 146:971-975(1987)

Limitation

For research use only

Related
products

Code	Product Name
OST00324W	Goat antibody to Tyrosine Hydroxylase (30-100)
OST00481W	Guinea pig antibody to Tyrosine Hydroxylase

Code

OST00323W

$260USD

Unit size

150 ul

Conjugate

Unconjugated antibody

Host

NZ white rabbit

Purity

Whole serum

Clonality

Polyclonal

Isotype

Polyclonal, whole serum

Applications

IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity

Specific for TH.

Spcs X-react.

Human, rat, mouse. Other species not yet tested.

Format

Lyophilised

Reconstitution

Reconstitute in 150 ul of sterile water. Centrifuge to remove any insoluble material.

Note

Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code

OST00323W