⚬ Services
Code
OSS00179W
$240USD    Buy Now 

ID Tag
Rb1136-260909-WS

Immunogen
A synthetic peptide from aa region 595-645of human Synapsin 1 conjugated to blue carrier protein was used as the antigen.

Accession

Also known
Synapsin 1, Syn1, Synapsin I

Target
May act as an anchoring protein by linking the vesicle phospholipid layer and the cytoskeleton in neuronal presynaptic terminals; may play a role in neurotransmitter release.
FUNCTION: Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. Defects in SYN1 are a cause of epilepsy X-linked with variable learning disabilities and behavior disorders. XELBD is characterized by variable combinations of epilepsy, learning difficulties, macrocephaly, and aggressive behavior.
SUBCELLULAR LOCATION: Cell junction, synapse. Golgi apparatus.

Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date
12 months after reconstitution

Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.

References
1. Ross M.T, et al. Nature 434:325-337(2005)
2. Matsuoka S, et al. Science 316:1160-1166(2007)

Limitation
For research use only

Code
OSS00179W
$240USD    Buy Now 

Unit size
100 µl

Conjugate
Unconjugated antibody

Host
NZ white rabbit

Purity
Whole serum

Clonality
Polyclonal

Isotype
Polyclonal, whole serum

Applications
IHC, WB. A dilution of 1 : 2000 to 1 : 4000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Specificity
Specific for Synapsin-1.

Spcs X-react.
Human, rat, mouse. Other species not yet tested.

Format
Lyophilised

Reconstitution
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.

Note
Control peptide is available at $120 per 50 μg. Please enquire sales@osenses.com

Code
OSS00179W
$240USD    Buy Now 


Rabbit antibody to Synapsin 1 (595-645) WB on brain  lysates. Blocking with 1% LFDM for 30 min at RT; Primary antibody used at 1:3000 dilution incubated overnight at 4C. Click on eLAB BOOK tab to see the details.

⚬ Products
Rabbit antibody to Synapsin 1 (595-645)
Content

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APES coating of slides
SDS Loading Buffer
IHC-P on Autostainer
G1 Lysing Buffer
WB Protocol online
IHC-P HIER (Tris-EDTA, pH 9)
4% PFA
Davidson's fix (modified)
....Tissue lysate perparation
....G2 Lysing Buffer
....R Lysing Buffer
....G3 Lysing Buffer
....G4 Lysing Buffer
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.G6 Lysing Buffer
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