A synthetic peptide from mouse Catalase conjugated to blue carrier protein was used as the antigen. The antigen is homologous in many other species including rat, human, marmoset, zebrafish, xenopus and guinea pig.
FUNCTION: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
Defects in CAT are the cause of acatalasia (ACATLAS); also known as acatalasemia. This disease is characterized by absence of catalase activity in red cells and is often associated with ulcerating oral lesions.
SUBCELLULAR LOCATION: Peroxisome
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
12 months after reconstitution
This item will be shipped to you at ambient temperature in a lyophilised form.
1. Quan F, et al. Nucleic Acids Res. 14:5321-5335(1986)
For research use only
NZ white rabbit
Polyclonal, whole serum
IHC, WB. A dilution of 1: 2000 is recommended for IHC-P and 1: 7000 for WB. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Specific for Catalase.
Mouse, rat, human, xenopus, zebrafish. Not yet tested in other species.
Reconstitute in 100 µl of sterile water. Centrifuge to remove any insoluble material.